User blog comment:Yuka Ichinose/Pixel Art/@comment-27761674-20151027050223/@comment-26662455-20151029051323

This is just basically from my experience in using both:

If you want an app that is simple and quite easy to move around with, I suggest GIMP. Although it doesn't provide as much as many tools as PS does. PS, on the other hand, is a bit more complicated than GIMP, but gives you more options when it comes to the toold you use and modifications -- or whatever stuff. Artists usually prefer PS over GIMP.